Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735971 | 0.85 | MEN1 (0.61) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL8067767 | 0.83 | MEN1 (0.59) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL887723 | 0.80 | MAPT (0.56) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL31531064 | 0.80 | MEN1 (0.56) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL241952 | 0.80 | MEN1 (0.56) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL28628097 | 0.80 | MEN1 (0.56) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL30060467 | 0.77 | MEN1 (0.61) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL9663555 | 0.77 | MAPT (0.61) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL9199234 | 0.77 | MEN1 (0.61) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL1010648 | 0.77 | MEN1 (0.53) | KMT2AMEN1MAPTCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |