Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | PLK1 | P53350 | 5/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080660 | 0.85 | MEN1 (0.57) | PTPN1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL23924441 | 0.84 | PTPN1 (0.75) | PTPN1PLK1PLK3NPSR1KMT2A | |
| SCHEMBL29406212 | 0.84 | PTPN1 (0.75) | PTPN1PLK1PLK3NPSR1KMT2A | |
| SCHEMBL8081846 | 0.83 | LMNA (0.60) | PTPN1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL8085142 | 0.83 | LMNA (0.60) | PTPN1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL8072260 | 0.83 | LMNA (0.60) | PTPN1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL8081832 | 0.83 | LMNA (0.60) | PTPN1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL8086789 | 0.83 | LMNA (0.60) | PTPN1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL9417688 | 0.83 | LMNA (0.60) | PTPN1NPSR1KMT2AMEN1LMNA | |
| SCHEMBL17090798 | 0.83 | LMNA (0.60) | PTPN1NPSR1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380181-B1 | AMINO ACID RESIDUES IN THE 3-AND/OR 4-POSITION FUNCTION AS SIDEROPHORES AND/OR AS BIOLOGICAL CHELATING AGENTS FOR IRON IN GRAM-NEGATIVE BACTERIA | GRUENENTHAL GMBH (DE) | 2002-04-30 | — | — | US | disclosed |