Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881424 | 1.00 | MGLL (0.44) | MGLLCHRNA7BRAFKDRCHRNB2 | |
| SCHEMBL6882908 | 0.87 | BRAF (0.45) | MGLLCHRNA7BRAFKDRCHRNB2 | |
| SCHEMBL6881381 | 0.87 | CHRNA7 (0.45) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6879331 | 0.86 | CHRNA7 (0.44) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6874193 | 0.86 | CHRNA7 (0.45) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6880056 | 0.84 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6883249 | 0.84 | CHRNA7 (0.45) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6882957 | 0.84 | CHRNA7 (0.46) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6881334 | 0.83 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6881945 | 0.83 | CHRNA7 (0.48) | CHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016356-A2 | QUINUCLIDINE-SUBSTITUTED ARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |