Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 18/20 | 0.75 |
| ▸ | ADRB3 | P13945 | 18/20 | 0.75 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092786 | 1.00 | ADRB1 (0.75) | ADRB1ADRB3ADRB2LMNANFKB1 | |
| SCHEMBL7096001 | 0.87 | ADRB3 (0.80) | ADRB1ADRB3ADRB2LMNANFKB1 | |
| SCHEMBL7094015 | 0.86 | ADRB1 (0.61) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7091566 | 0.86 | ADRB3 (1.00) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7094287 | 0.86 | ADRB3 (0.57) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7703076 | 0.85 | ADRB3 (0.77) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7094213 | 0.85 | ADRB3 (0.77) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7091417 | 0.85 | ADRB3 (0.77) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7095333 | 0.85 | ADRB3 (0.76) | ADRB1ADRB3ADRB2LMNANFKB1 | |
| SCHEMBL7091306 | 0.80 | ADRB3 (0.88) | ADRB1ADRB3ADRB2LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |