Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700027 | 0.78 | SMN1; SMN2 (0.50) | POLBCYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL7700999 | 0.78 | MAPT (0.48) | CDC7CCNE1CDK2DBF4POLB | |
| SCHEMBL7705421 | 0.78 | CNR1 (0.50) | GSK3BROCK2PRKCGPRKCD | |
| SCHEMBL30106340 | 0.77 | CDC25A (0.47) | POLBMAPK1HPGDNPSR1TP53 | |
| SCHEMBL7693805 | 0.77 | KDM4E (0.58) | POLBGSK3BROCK2ROCK1HPGD | |
| SCHEMBL7701209 | 0.75 | NPC1 (0.51) | CDC7DBF4POLBMAPK1TSHR | |
| SCHEMBL7697807 | 0.74 | GPBAR1 (0.47) | POLBMAPK1CYP1A2CYP2C9HPGD | |
| SCHEMBL11623795 | 0.73 | GAA (0.60) | POLBMAPK1TSHRTHRBKDM4E | |
| SCHEMBL29158752 | 0.73 | BCL2L1 (0.52) | ABCB1TSHRHPGDTP53ALDH1A1 | |
| SCHEMBL6370461 | 0.72 | ERAP1 (0.47) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |