Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4487202 | 0.93 | IKBKB (0.56) | NPC1RAB9AIKBKBSMN1; SMN2KDM4E | |
| SCHEMBL3128951 | 0.84 | IKBKB (0.54) | NPC1RAB9AIKBKBPKMSMN1; SMN2 | |
| SCHEMBL7695337 | 0.84 | IKBKB (0.55) | NPC1RAB9AIKBKBSMN1; SMN2KDM4E | |
| SCHEMBL3127884 | 0.81 | IKBKB (0.56) | NPC1RAB9AIKBKBSMN1; SMN2KDM4E | |
| SCHEMBL7699801 | 0.81 | ALDH1A1 (0.51) | NPC1RAB9AIKBKBPKMSMN1; SMN2 | |
| SCHEMBL7699490 | 0.81 | TARBP2 (0.67) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL3124862 | 0.80 | IKBKB (0.71) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL1167163 | 0.79 | NAPRT (0.38) | NPC1RAB9AATAD2PKMMAPK13 | |
| SCHEMBL7693588 | 0.79 | KDM4E (0.65) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6366044 | 0.79 | NPC1 (0.55) | NPC1IKBKBDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |