Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697996 | 1.00 | PRCP (0.69) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL30973183 | 0.82 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL22728763 | 0.82 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL28277290 | 0.82 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL7214001 | 0.82 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL327233 | 0.81 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL30721685 | 0.81 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL12046710 | 0.81 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL29478499 | 0.81 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 | |
| SCHEMBL325083 | 0.81 | PRCP (1.00) | PRCPGAAGID4RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0901488-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| US-5866583-A | Substituted 2,4-diaminopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1997043277-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-20 | — | — | WO | disclosed |