Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12049968 | 0.81 | HRH3 (0.38) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL12841653 | 0.79 | — | — | |
| SCHEMBL12030698 | 0.79 | HRH3 (0.42) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL24300093 | 0.76 | CTSV (0.33) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL18704890 | 0.76 | HTT (0.36) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL15888619 | 0.76 | PIK3CA (0.34) | — | |
| SCHEMBL12606264 | 0.75 | — | — | |
| SCHEMBL8077669 | 0.75 | NPC1 (0.37) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL15039837 | 0.74 | MEN1 (0.33) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL19438366 | 0.74 | MEN1 (0.33) | CTSVCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2011143365-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |