Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 10/20 | 0.46 |
| ▸ | PDE4A | P27815 | 8/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713389 | 0.99 | HTR2C (0.47) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| Hydrochloric Acid SCHEMBL8710356 | 0.98 | HTR2C (0.46) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL8714617 | 0.91 | HTR2C (0.47) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL8708977 | 0.89 | HTR2C (0.49) | HTR2C | |
| SCHEMBL8711334 | 0.88 | HTR2C (0.41) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7700449 | 0.88 | PDE4D (0.43) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL8711289 | 0.87 | PDE4A (0.46) | PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8710772 | 0.86 | PDE4A (0.45) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7694316 | 0.84 | HTR2C (0.61) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL8707421 | 0.83 | HTR2C (0.46) | PDE4DPDE4APDE4BPDE4CHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081447-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOTHIAZOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |