Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.43 |
| ▸ | PDE4A | P27815 | 13/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698109 | 0.88 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7700756 | 0.88 | LMNA (0.47) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7692634 | 0.87 | PDE4B (0.45) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL8713389 | 0.87 | HTR2C (0.47) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7693683 | 0.86 | PDE4A (0.45) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7701694 | 0.86 | PDE4A (0.44) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7699545 | 0.86 | HTR2C (0.42) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| Hydrochloric Acid SCHEMBL8710356 | 0.86 | HTR2C (0.46) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7700521 | 0.85 | PDE4A (0.42) | PDE4DPDE4APDE4BPDE4CHTR2C | |
| SCHEMBL7701516 | 0.81 | MCHR1 (0.42) | PDE4DPDE4APDE4BPDE4CHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |