Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.58 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.58 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.58 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.58 |
| ▸ | S100A4 | P26447 | 5/20 | 0.55 |
| ▸ | NSD2 | O96028 | 5/20 | 0.54 |
| ▸ | TDP2 | O95551 | 3/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695343 | 0.94 | S100A4 (0.58) | PADI1PADI3PADI4PADI2S100A4 | |
| SCHEMBL7694672 | 0.81 | CDC25B (0.65) | S100A4NSD2TDP2PAX8ABL1 | |
| SCHEMBL7693731 | 0.79 | CDC25B (0.66) | S100A4NSD2TDP2PAX8ABL1 | |
| SCHEMBL7692908 | 0.79 | CDC25B (0.71) | S100A4NSD2TDP2PAX8ABL1 | |
| SCHEMBL7692775 | 0.78 | CDC25B (0.67) | S100A4NSD2TDP2PAX8ABL1 | |
| SCHEMBL7696446 | 0.78 | CDC25B (0.65) | PADI1PADI3PADI4PADI2S100A4 | |
| SCHEMBL17250406 | 0.76 | NSD2 (0.68) | S100A4NSD2TDP2CDC25BATG4B | |
| SCHEMBL3295164 | 0.75 | S100A4 (0.59) | S100A4NSD2TDP2PAX8ABL1 | |
| SCHEMBL30292918 | 0.75 | S100A4 (0.59) | S100A4NSD2TDP2PAX8ABL1 | |
| SCHEMBL7696959 | 0.74 | NSD2 (0.56) | S100A4NSD2TDP2HKDC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002034742-A1 | AZIRIDINYLQUINOLINEDIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-05-02 | — | — | WO | claimed |
| WO-2002034742-A1 | AZIRIDINYLQUINOLINEDIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-05-02 | — | — | WO | disclosed |