Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693959 | 0.89 | MAPT (0.52) | HSD17B10TSHRMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7701071 | 0.87 | TSHR (0.63) | HSD17B10TSHRALOX15MAPTKDM4E | |
| SCHEMBL7700032 | 0.84 | NPC1 (0.55) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7697323 | 0.83 | RAB9A (0.57) | HSD17B10ALOX15MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7704827 | 0.82 | NPC1 (0.55) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7695399 | 0.81 | KDM4E (0.51) | HSD17B10TSHRMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7705439 | 0.80 | KDM4E (0.50) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7698117 | 0.80 | NPC1 (0.57) | HSD17B10TSHRKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8711039 | 0.79 | F2 (0.72) | TSHRSMN1; SMN2ALDH1A1NPSR1TP53 | |
| SCHEMBL7700066 | 0.78 | NPC1 (0.58) | HSD17B10TSHRALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |