Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698519 | 0.97 | HTT (0.63) | HTTHDAC8HDAC6CYP2D6CYP2C9 | |
| SCHEMBL4612423 | 0.83 | HTT (0.77) | HTTHDAC8HDAC6CYP2D6CYP2C9 | |
| SCHEMBL7697402 | 0.81 | HTT (0.58) | HTTHDAC8HDAC6CYP2D6CYP2C9 | |
| SCHEMBL6946370 | 0.77 | HTT (0.68) | HTTHDAC8HDAC6CYP2D6CYP2C9 | |
| SCHEMBL279859 | 0.77 | HTT (0.63) | HTTHDAC8HDAC6CYP2D6CYP2C9 | |
| SCHEMBL2399935 | 0.75 | HTT (0.96) | HTTHDAC8HDAC6CYP2C9CYP2C19 | |
| SCHEMBL4041565 | 0.75 | HTT (0.59) | HTTHDAC8HDAC6CYP2D6CYP2C9 | |
| SCHEMBL1196393 | 0.75 | SMN1; SMN2 (0.63) | HTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL7375838 | 0.74 | LMNA (0.38) | HDAC8HDAC6CYP2D6CYP2C9CYP2C19 | |
| N-Piperidinobenzamide SCHEMBL696161 | 0.74 | HTT (1.00) | HTTCYP2C9SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |