Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234357 | 0.87 | MEN1 (0.53) | MEN1KMT2AMMP8GAAMGAM | |
| SCHEMBL28125259 | 0.86 | MEN1 (0.42) | MEN1KMT2AMMP8HTTHPGD | |
| SCHEMBL7781952 | 0.84 | MMP8 (0.50) | MEN1KMT2AMMP8GAAMGAM | |
| SCHEMBL28077465 | 0.84 | MEN1 (0.46) | MEN1KMT2AMMP8GAAMGAM | |
| SCHEMBL7781947 | 0.82 | MEN1 (0.49) | MEN1KMT2AMMP8HTTHPGD | |
| SCHEMBL14743485 | 0.82 | MMP8 (0.49) | MEN1KMT2AMMP8GAAMGAM | |
| SCHEMBL9788191 | 0.82 | MEN1 (0.47) | MEN1KMT2AGAAMGAMSI | |
| SCHEMBL17785936 | 0.81 | MMP8 (0.38) | MEN1KMT2AMMP8GAAMGAM | |
| SCHEMBL10992850 | 0.81 | GAA (0.50) | MEN1KMT2AGAAMGAMSI | |
| SCHEMBL7777122 | 0.79 | MEN1 (0.46) | MEN1KMT2AMMP8HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |