Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7702945 | 0.84 | KCNH2 (0.70) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL7697513 | 0.81 | KCNH2 (0.62) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL7695498 | 0.80 | KCNH2 (0.61) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL7697484 | 0.76 | KCNH2 (0.49) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL7699375 | 0.76 | KCNH2 (0.49) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL7697481 | 0.76 | KCNH2 (0.49) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL7701103 | 0.75 | KCNH2 (0.48) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL7696256 | 0.75 | KCNH2 (0.48) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL7696254 | 0.75 | KCNH2 (0.48) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9504578 | 0.74 | DRD2 (0.66) | DRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037871-B1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET (HU) | 2002-07-03 | — | — | EP | disclosed |
| US-6265445-B1 | CARDIOVASCULAR DISORDERS | GYOGYSZERKUTATO INTEZET KFT (HU) | 2001-07-24 | — | — | US | disclosed |
| EP-1037871-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029655-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 1999-06-17 | — | — | WO | disclosed |