Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.58 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL23068684 | 0.86 | CTNNB1 (0.74) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL27491890 | 0.86 | PARP10 (0.58) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL2661681 | 0.86 | PARP10 (0.58) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL15317994 | 0.85 | POLB (0.58) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL11780068 | 0.85 | POLB (0.58) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL27991134 | 0.84 | PARP10 (0.56) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL27486214 | 0.84 | PARP10 (0.61) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL920637 | 0.84 | PARP10 (0.56) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL28039268 | 0.84 | PARP10 (0.56) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL28260959 | 0.84 | PARP10 (0.56) | PARP10SIRT2SIRT1CTNNB1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |