Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.58 |
| ▸ | IKBKB | O14920 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31151866 | 0.91 | NR4A1 (0.52) | PARP10IKBKBSIRT2SIRT1HDAC3 | |
| SCHEMBL25328315 | 0.91 | NR4A1 (0.52) | PARP10IKBKBSIRT2SIRT1HDAC3 | |
| SCHEMBL28250577 | 0.89 | HDAC3 (0.55) | PARP10SIRT2SIRT1HDAC3BRAF | |
| SCHEMBL2949574 | 0.88 | PARP10 (0.59) | PARP10IKBKBSIRT2SIRT1HDAC3 | |
| SCHEMBL5078313 | 0.88 | POLB (0.57) | PARP10SIRT2SIRT1HDAC3BRAF | |
| SCHEMBL7764582 | 0.87 | MAOB (0.53) | PARP10IKBKBSIRT2SIRT1HDAC3 | |
| SCHEMBL27491890 | 0.86 | PARP10 (0.58) | PARP10IKBKBSIRT2SIRT1CTNNB1 | |
| SCHEMBL7698386 | 0.86 | PARP10 (0.61) | PARP10SIRT2SIRT1CTNNB1PARP15 | |
| SCHEMBL2723179 | 0.82 | ALDH1A1 (0.57) | PARP10SIRT2SIRT1HDAC3BRAF | |
| SCHEMBL1554060 | 0.82 | KMT2A (0.59) | PARP10HDAC3BRAFHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496052-A1 | NOVEL AMINOBENZAMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-01-12 | — | — | EP | disclosed |