Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 15/20 | 0.77 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CALML3 | P27482 | 1/20 | 0.51 |
| ▸ | SDHA | P31040 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696828 | 0.88 | MAOA (0.77) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL5218335 | 0.87 | MAOA (1.00) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7694226 | 0.86 | MAOA (0.75) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7695189 | 0.86 | MAOA (0.85) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7689362 | 0.86 | MAOA (0.74) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL5218343 | 0.85 | MAOA (0.84) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL5218330 | 0.85 | MAOA (0.84) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7696844 | 0.85 | MAOA (0.73) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6398400 | 0.82 | MAOA (0.78) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6396636 | 0.82 | MAOA (0.84) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080841-A2 | ANTIBACTERIAL OXAZOLIDINONES WITH A CYCLIC SULPHILIMINE OR SULPHOXIMINE | ASTRAZENECA AB (SE) | 2002-10-17 | — | — | WO | claimed |