SCHEMBL7698445

SCHEMBL7698445

Cc1ccc(Nc2cnc3cc4ccccc4cc3n2)cc1C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 7/20 0.68
PDGFRA P16234 6/20 0.68
RAB9A P51151 7/20 0.48
MAPT P10636 6/20 0.48
NPC1 O15118 6/20 0.48
KMT2A Q03164 5/20 0.48
KDM4E B2RXH2 2/20 0.48
GAA P10253 2/20 0.48
PKM P14618 1/20 0.48
RHOA P61586 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.44
TAAR1 Q96RJ0 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 3/20 0.42
ALDH1A1 P00352 1/20 0.42
CASP3 P42574 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
PIK3CA P42336 1/20 0.42
MAPK8 P45983 1/20 0.42
MAPK9 P45984 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7694730 0.87 PDGFRB (0.59) PDGFRBPDGFRARAB9AMAPTNPC1
SCHEMBL7696819 0.85 PDGFRB (0.68) PDGFRBPDGFRARAB9AMAPTNPC1
SCHEMBL7696400 0.81 PDGFRB (0.76) PDGFRBPDGFRARAB9AMAPTNPC1
SCHEMBL7696721 0.80 KMT2A (0.53) RAB9AMAPTNPC1KMT2AKDM4E
SCHEMBL7694543 0.79 PDGFRB (0.52) PDGFRBPDGFRARAB9ANPC1KMT2A
SCHEMBL7697715 0.79 PDGFRB (0.52) PDGFRBPDGFRARAB9ANPC1KMT2A
SCHEMBL7692274 0.79 PDGFRB (0.71) PDGFRBPDGFRAMAPTPIK3CAKDR
SCHEMBL7695393 0.79 PDGFRB (0.59) PDGFRBPDGFRARAB9AMAPTNPC1
SCHEMBL6215798 0.79 PDGFRB (0.72) PDGFRBPDGFRARAB9AMAPTNPC1
SCHEMBL7696743 0.79 PDGFRB (0.59) PDGFRBPDGFRARAB9AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002094796-A2 BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES AXXIMA PHARMACEUTICALS AG (DE) 2002-11-28 WO disclosed