Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699572 | 0.82 | PDE10A (0.32) | PDE10A | |
| SCHEMBL14440476 | 0.77 | CHRNB4 (0.31) | PDE10A | |
| SCHEMBL14440474 | 0.77 | CHRNB4 (0.31) | PDE10A | |
| SCHEMBL19174251 | 0.76 | OPRL1 (0.33) | PDE10A | |
| SCHEMBL17668897 | 0.76 | PDE10A (0.32) | PDE10A | |
| SCHEMBL1304488 | 0.72 | OPRL1 (0.35) | — | |
| SCHEMBL7699577 | 0.71 | CHRNB2 (0.42) | — | |
| SCHEMBL11679373 | 0.71 | OPRL1 (0.37) | — | |
| SCHEMBL1303092 | 0.70 | POLB (0.50) | PDE10A | |
| SCHEMBL2634421 | 0.69 | SSTR4 (0.32) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143365-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |