Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | FES | P07332 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991102 | 0.89 | DYRK1A (0.56) | DYRK1AKDM4ETSHRMAPK1HTT | |
| SCHEMBL7699589 | 0.88 | DYRK1A (0.55) | DYRK1ASRCKDM4ETSHRMAPK1 | |
| SCHEMBL7701084 | 0.87 | DYRK1A (0.53) | DYRK1ASRCKDM4ETSHRMAPK1 | |
| SCHEMBL7702638 | 0.86 | DYRK1A (0.51) | DYRK1ASRCKDM4ETSHRMAPK1 | |
| SCHEMBL7695781 | 0.84 | DYRK1A (0.56) | DYRK1ASRCKDM4ETSHRMAPK1 | |
| SCHEMBL7695831 | 0.83 | DYRK1A (0.46) | DYRK1AKDM4ETSHRMAPK1HTT | |
| SCHEMBL7702669 | 0.82 | DYRK1A (0.57) | DYRK1ASRCKDM4ETSHRMAPK1 | |
| SCHEMBL7697867 | 0.82 | DYRK1A (0.54) | DYRK1AKDM4ETSHRMAPK1HTT | |
| SCHEMBL7701007 | 0.79 | DYRK1A (0.54) | DYRK1ASRCKDM4ETSHRMAPK1 | |
| SCHEMBL7699827 | 0.79 | DYRK1A (0.54) | DYRK1ASRCKDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |