Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.78 |
| ▸ | MAOA | P21397 | 15/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15839887 | 0.87 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL948052 | 0.85 | MAOB (0.93) | MAOBMAOA | |
| SCHEMBL226640 | 0.84 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL6825904 | 0.84 | MAOB (0.67) | MAOBMAOAHRH3 | |
| SCHEMBL17703887 | 0.84 | MAOB (0.67) | MAOBMAOAHRH3 | |
| SCHEMBL1377016 | 0.84 | MAOB (0.69) | MAOBMAOAHRH3 | |
| SCHEMBL9222772 | 0.84 | MAOB (0.69) | MAOBMAOAHRH3 | |
| SCHEMBL6172712 | 0.84 | MAOB (0.67) | MAOBMAOAHRH3 | |
| SCHEMBL12901556 | 0.83 | MAOA (0.65) | MAOBMAOA | |
| SCHEMBL30966017 | 0.83 | MAOA (0.65) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |