Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692903 | 0.89 | NR1H3 (0.45) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7699466 | 0.85 | PDE4A (0.40) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7699505 | 0.83 | NR1H3 (0.49) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7694958 | 0.81 | NR1H3 (0.44) | PDE4APDE4BPDE4CPDE4DNR1H2 | |
| SCHEMBL8708142 | 0.81 | RAB9A (0.51) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8711302 | 0.80 | HTR2C (0.44) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8708036 | 0.80 | QPCT (0.48) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8707222 | 0.79 | MCHR1 (0.45) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8712042 | 0.79 | NR1H3 (0.42) | PDE4APDE4BPDE4CPDE4DNR1H2 | |
| SCHEMBL7703112 | 0.77 | NR1H2 (0.38) | PDE4APDE4BPDE4CPDE4DNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |