Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.41 |
| ▸ | PDE4A | P27815 | 10/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711406 | 0.91 | HTR2C (0.47) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8711442 | 0.90 | HTR2C (0.48) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL7693264 | 0.85 | HTR2C (0.49) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8712165 | 0.83 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8713066 | 0.83 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8711413 | 0.82 | HTR2C (0.50) | HTR2CHTR2APOLBHTR2B | |
| SCHEMBL8708944 | 0.82 | HTR2C (0.45) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL7700756 | 0.80 | LMNA (0.47) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL8710723 | 0.79 | HTR2C (0.47) | PDE4BPDE4APDE4CPDE4DHTR2C | |
| SCHEMBL7693887 | 0.79 | HTR2C (0.49) | PDE4BPDE4APDE4CPDE4DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |