Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696679 | 0.88 | MAPT (0.42) | ALDH1A1TP53MAPTTSHRKMT2A | |
| SCHEMBL7695041 | 0.85 | TP53 (0.47) | ALDH1A1PLA2G1BNPSR1ATG4BTP53 | |
| SCHEMBL7698858 | 0.84 | MAPT (0.57) | ALDH1A1NPSR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL7696766 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TP53MAPTSMN1; SMN2TSHR | |
| SCHEMBL7701098 | 0.77 | ALDH1A1 (0.37) | ALDH1A1NPSR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL7696676 | 0.76 | TP53 (0.43) | ALDH1A1NPSR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL7701107 | 0.75 | C1R (0.46) | ALDH1A1NPSR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL7698770 | 0.75 | MAPT (0.61) | ALDH1A1TP53MAPTTSHRKMT2A | |
| SCHEMBL7694774 | 0.74 | MAPT (0.41) | ALDH1A1TP53MAPTKMT2AHPGD | |
| SCHEMBL7696896 | 0.74 | KMT2A (0.41) | ALDH1A1PLA2G1BNPSR1ATG4BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |