Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 3/20 | 0.46 |
| ▸ | NPY1R | P25929 | 2/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413420 | 0.95 | PTGER4 (0.58) | PTGER4CTSSSIRT5CTSL | |
| SCHEMBL7358758 | 0.95 | PTGER4 (0.58) | PTGER4CTSSSIRT5CTSL | |
| SCHEMBL5419016 | 0.92 | PTGER4 (0.55) | PTGER4CTSKCTSSCTSLCTSB | |
| SCHEMBL8495773 | 0.92 | PTGER4 (0.55) | PTGER4CTSKCTSSCTSLCTSB | |
| SCHEMBL7355085 | 0.92 | PTGER4 (0.55) | PTGER4CTSKCTSSCTSLCTSB | |
| SCHEMBL14968961 | 0.88 | PTGER4 (0.51) | PTGER4PSMB1CAPN1CAPN2CTSK | |
| SCHEMBL537968 | 0.86 | PTGER4 (0.55) | PTGER4 | |
| SCHEMBL3734177 | 0.83 | MAP1LC3B (0.42) | PTGER4CAPN1NPY4RNPY1RNPY2R | |
| SCHEMBL335479 | 0.83 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL9022219 | 0.82 | PTGER4 (0.46) | PTGER4NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346373-B1 | INCUBATING TRANSFORMED CELL WITH SUBSTRATE IN PRESENCE OF PROTEASE INHIBITOR; OSTEOPOROSIS, BONE DISORDERS | MERCK FROSST CANADA & CO., (CA) | 2002-02-12 | — | — | US | claimed |