SCHEMBL7698979

SCHEMBL7698979

CCC(C)(C)c1ccc(OCCCC(=O)Nc2ccc(Cl)c(NC(=O)C(Cl)C(=O)C(C)(C)C)c2)c(C(C)(C)CC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.41
MAPK1 P28482 3/20 0.41
NPSR1 Q6W5P4 3/20 0.41
MAPT P10636 4/20 0.40
POLB P06746 2/20 0.40
CDYL Q9Y232 1/20 0.40
CYP2C19 P33261 3/20 0.39
CYP2C9 P11712 1/20 0.39
HTT P42858 2/20 0.38
UBE2N P61088 2/20 0.38
GLA P06280 1/20 0.38
MITF O75030 1/20 0.38
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10886968 0.88 MEN1 (0.43) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL9340282 0.87 RAB9A (0.44) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL9344152 0.85 MEN1 (0.38) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL11343863 0.84 MEN1 (0.39) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL9340255 0.84 MEN1 (0.37) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL11586329 0.84 MEN1 (0.37) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL11819814 0.83 MEN1 (0.37) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL11820029 0.83 KMT2A (0.37) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL11817386 0.83 MEN1 (0.41) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1
SCHEMBL11822063 0.82 MAPT (0.41) MEN1KMT2AALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6346371-B1 SILVER CHLORIDE EMULSION; IMAGE DYE-FORMING COUPLER; HIGH SPEED PROCESSING EASTMAN KODAK COMPANY 2002-02-12 US disclosed
EP-1151353-A1 PHOTOGRAPHIC ELEMENT CONTAINING A DIR COUPLER EASTMAN KODAK COMPANY (US) 2001-11-07 EP disclosed
WO-2000038012-A1 PHOTOGRAPHIC ELEMENT CONTAINING A DIR COUPLER EASTMAN KODAK COMPANY (US) 2000-06-29 WO disclosed
US-4012259-A DICARBONYL METHYLENE GROUP ON A 2,5-DIOXO-1-IMIDAZOLIDINE IS A YELLOW COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-03-15 US disclosed