Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | PDE6A | P16499 | 1/20 | 0.37 |
| ▸ | PDE6G | P18545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26607350 | 0.81 | ALDH1A1 (0.36) | PDE3BPDE3AALDH1A1KDM4EMEN1 | |
| SCHEMBL26606925 | 0.81 | NQO2 (0.37) | ALDH1A1KDM4EHPGDNQO2MAPT | |
| SCHEMBL26607369 | 0.77 | NQO2 (0.39) | ALDH1A1KDM4EHPGDNQO2MAPT | |
| SCHEMBL13729067 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDNQO2MAPT | |
| SCHEMBL30573125 | 0.77 | NQO2 (0.39) | ALDH1A1KDM4EHPGDNQO2MAPT | |
| SCHEMBL7811233 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDNQO2MAPT | |
| SCHEMBL30509466 | 0.75 | SRC (0.51) | PDE3BPDE3ASRCALDH1A1KDM4E | |
| SCHEMBL26607384 | 0.75 | NQO2 (0.38) | ALDH1A1KDM4EGAANQO2MAPT | |
| SCHEMBL2210144 | 0.75 | SRC (0.51) | PDE3BPDE3ASRCALDH1A1KDM4E | |
| SCHEMBL7696835 | 0.73 | ALDH1A1 (0.61) | PDE3BPDE3ASRCALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |