SCHEMBL7699261

SCHEMBL7699261

C=CCNc1nnc(N)s1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
KDM4E B2RXH2 5/20 0.51
HPGD P15428 4/20 0.51
CCNA2 P20248 9/20 0.39
CDK2 P24941 9/20 0.39
CCNE1 P24864 1/20 0.39
MAPT P10636 6/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
NPC1 O15118 4/20 0.37
RAB9A P51151 4/20 0.37
KMT2A Q03164 2/20 0.37
NFKB1 P19838 2/20 0.37
NFKB2 Q00653 2/20 0.37
RELA Q04206 2/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11779167 0.85 ALDH1A1 (0.59) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL11575805 0.78 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL11035316 0.76 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL11509117 0.76 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL11584205 0.76 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL11576217 0.76 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL11443906 0.74 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL5493249 0.69 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDCCNA2CDK2
SCHEMBL5174001 0.69 F2 (0.34) ALDH1A1CYP2D6CYP2C19HTTHSD17B10
SCHEMBL11774009 0.69 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDCCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752128-A Preparation method of HDPE (high-density polyethylene) composite pipe material 江苏恒峰线缆有限公司 2022-07-15 CN claimed
EP-0272212-B1 PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES CIBA-GEIGY AG (CH) 1993-09-01 EP claimed
US-4925926-A Preparation of cationic azo or hydrazone dyes in which the alkylation and the separation of the cationic dye are carried out continuously CIBA-GEIGY CORPORATION (US) 1990-05-15 US claimed
EP-0272212-A2 Process for continually producing azo or hydrazone dyes CIBA-GEIGY AG (CH) 1988-06-22 EP claimed
CN-114752128-A Preparation method of HDPE (high-density polyethylene) composite pipe material 江苏恒峰线缆有限公司 2022-07-15 CN disclosed
CN-114752128-A Preparation method of HDPE (high-density polyethylene) composite pipe material 江苏恒峰线缆有限公司 2022-07-15 CN disclosed
US-6500842-B1 N-((4-CHLOROPHENYL)METHYL)-8-HYDROXY-7-QUINOLINECARBOXAMIDE ADMINISTERED AS VIRICIDES AGAINST HERPES VIRUS PHARMACIA & UPJOHN COMPANY 2002-12-31 US disclosed
US-6310211-B1 ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 PHARMACIA & UPJOHN COMPANY 2001-10-30 US disclosed
US-6252080-B1 HERPES, CYTOMEGALO VIRUS PHARMACIA & UPJOHN COMPANY 2001-06-26 US disclosed
US-6211376-B1 HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS PHARMACIA & UPJOHN COMPANY 2001-04-03 US disclosed
EP-0927164-A1 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 1999-07-07 EP disclosed
WO-1998011073-A1 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 1998-03-19 WO disclosed
EP-0272212-B1 PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES CIBA-GEIGY AG (CH) 1993-09-01 EP disclosed
US-4925926-A Preparation of cationic azo or hydrazone dyes in which the alkylation and the separation of the cationic dye are carried out continuously CIBA-GEIGY CORPORATION (US) 1990-05-15 US disclosed
EP-0272212-A2 Process for continually producing azo or hydrazone dyes CIBA-GEIGY AG (CH) 1988-06-22 EP disclosed
US-4500715-A CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES BAYER AKTIENGESELLSCHAFT (DE) 1985-02-19 US disclosed
US-4268438-A Cationic 1,3,4-thiadiazole dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed