Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.71 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.71 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | FADS1 | O60427 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952287 | 0.88 | PDGFRB (0.68) | PDGFRBPDGFRAIGF1RHTR3EHTR3B | |
| SCHEMBL7696498 | 0.87 | PDGFRB (0.55) | PDGFRBPDGFRAIGF1RHTR3EHTR3B | |
| SCHEMBL6213709 | 0.87 | PDGFRB (0.74) | PDGFRBPDGFRAIGF1RHTR3EHTR3B | |
| SCHEMBL7695393 | 0.85 | PDGFRB (0.59) | PDGFRBPDGFRAABCG2EGFRERBB3 | |
| SCHEMBL7696400 | 0.84 | PDGFRB (0.76) | PDGFRBPDGFRAABCG2MEN1KMT2A | |
| SCHEMBL3911063 | 0.83 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRERBB3MEN1 | |
| SCHEMBL7694543 | 0.82 | PDGFRB (0.52) | PDGFRBPDGFRAIGF1RKMT2AKDR | |
| SCHEMBL7697848 | 0.82 | PDGFRB (0.56) | PDGFRBPDGFRAABCG2ABCC1EGFR | |
| SCHEMBL7691917 | 0.82 | PDGFRB (0.56) | PDGFRBPDGFRAABCG2ABCB1ABCC1 | |
| SCHEMBL7699307 | 0.82 | PDGFRB (0.56) | PDGFRBPDGFRAIGF1RABCG2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |