Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | RHOA | P61586 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696400 | 0.84 | PDGFRB (0.76) | PDGFRBPDGFRAABCG2RHOANPC1 | |
| SCHEMBL7691917 | 0.82 | PDGFRB (0.56) | PDGFRBPDGFRAABCG2EGFRRHOA | |
| SCHEMBL7699322 | 0.82 | PDGFRB (0.71) | PDGFRBPDGFRAABCG2EGFRRHOA | |
| SCHEMBL7697848 | 0.82 | PDGFRB (0.56) | PDGFRBPDGFRAABCG2EGFRRHOA | |
| SCHEMBL7697737 | 0.79 | CTSC (0.45) | PDGFRBPDGFRA | |
| SCHEMBL7697641 | 0.79 | AURKA (0.54) | PDGFRBPDGFRAABCG2EGFR | |
| SCHEMBL7694543 | 0.77 | PDGFRB (0.52) | PDGFRBPDGFRARHOANPC1RAB9A | |
| SCHEMBL7698445 | 0.77 | PDGFRB (0.68) | PDGFRBPDGFRARHOANPC1RAB9A | |
| SCHEMBL7697715 | 0.77 | PDGFRB (0.52) | PDGFRBPDGFRARHOANPC1RAB9A | |
| SCHEMBL7696743 | 0.76 | PDGFRB (0.59) | PDGFRBPDGFRAABCG2RHOANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |