Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7698306 | 0.99 | SLC5A7 (0.54) | SLC5A7HRH3OPRK1MEN1KMT2A | |
| SCHEMBL6487958 | 0.87 | KMT2A (0.51) | SLC5A7OPRK1MEN1KMT2ANPC1 | |
| SCHEMBL2811871 | 0.87 | SLC5A7 (0.57) | SLC5A7HRH3OPRK1MEN1KMT2A | |
| SCHEMBL4237314 | 0.84 | HRH3 (0.57) | SLC5A7HRH3OPRK1MEN1KMT2A | |
| SCHEMBL931742 | 0.84 | MAOA (0.52) | OPRK1MEN1KMT2ARAB9A | |
| SCHEMBL930973 | 0.84 | MAOA (0.49) | OPRK1MEN1KMT2ARAB9A | |
| SCHEMBL6975866 | 0.83 | SLC5A7 (0.56) | SLC5A7HRH3OPRK1 | |
| Hydrochloric Acid SCHEMBL7081383 | 0.83 | HRH3 (0.56) | SLC5A7HRH3OPRK1MEN1KMT2A | |
| SCHEMBL931352 | 0.83 | MAOA (0.54) | OPRK1MEN1KMT2ARAB9A | |
| SCHEMBL930417 | 0.83 | MAOA (0.54) | OPRK1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455520-B1 | TUMOR NECROSIS FACTOR AND INTERLEUKIN INHIBITORS; ANTIINFLAMMATORY AGENTS, ANTIALLERGENS; BONE DISORDERS | ASTRA ZENECA AB (SE) | 2002-09-24 | — | — | US | disclosed |