Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900625 | 0.86 | ALOX15 (0.61) | ALOX15EPHX2ALDH1A1DGKA | |
| SCHEMBL8664640 | 0.86 | ALOX15 (0.61) | ALOX15EPHX2ALDH1A1DGKA | |
| SCHEMBL2171493 | 0.86 | ALOX15 (0.61) | ALOX15EPHX2ALDH1A1DGKA | |
| SCHEMBL19242397 | 0.86 | ALOX15 (0.61) | ALOX15EPHX2ALDH1A1DGKA | |
| SCHEMBL560301 | 0.85 | ALOX15 (0.63) | ALOX15EPHX2ALDH1A1USP2DGKA | |
| SCHEMBL6563202 | 0.84 | ALOX15 (0.58) | ALOX15EPHX2ALDH1A1USP2DGKA | |
| SCHEMBL9162630 | 0.82 | ALOX15 (0.56) | ALOX15EPHX2ALDH1A1DGKA | |
| SCHEMBL9162617 | 0.82 | ALOX15 (0.56) | ALOX15EPHX2ALDH1A1DGKA | |
| SCHEMBL9162610 | 0.82 | ALOX15 (0.56) | ALOX15EPHX2ALDH1A1DGKA | |
| SCHEMBL7705378 | 0.82 | ALOX15 (0.56) | ALOX15EPHX2ALDH1A1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348618-B1 | PREPARING ORGANOLEPTIC OR ANTIMICROBIAL COMPOUNDS BY CONTACTING BETA-KETO ESTER WITH MATERIAL SELECTED FROM BACTERIA, ENZYMES, AND MATERIAL HAVING ACIDIC OR ALKALINE PH, ELEVATING TEMPERATURE, EXPOSING TO LIGHT | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2002-02-19 | — | — | US | disclosed |
| US-6222062-B1 | USEFUL AS PRECURSORS FOR ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES AND MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2001-04-24 | — | — | US | disclosed |
| EP-1090624-A2 | Beta ketoester | Givaudan SA (CH) | 2001-04-11 | — | — | EP | disclosed |
| EP-0911315-A1 | Beta-ketoester | Givaudan Roure (International) S.A. (CH) | 1999-04-28 | — | — | EP | disclosed |