SCHEMBL7699463

SCHEMBL7699463

CCN1CCC/C(=N\OC)C1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.39
KMT2A Q03164 1/20 0.39
HRH3 Q9Y5N1 6/20 0.35
CHRM3 P20309 4/20 0.34
CHRM2 P08172 3/20 0.31
CHRM1 P11229 3/20 0.31
CHRM4 P08173 2/20 0.31
CHRM5 P08912 2/20 0.31
PNMT P11086 1/20 0.30
RAD52 P43351 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699465 1.00 CYP2D6 (0.39) CYP2D6KMT2AHRH3CHRM3CHRM2
SCHEMBL14155722 0.78 CYP2D6 (0.42) CYP2D6KMT2AHRH3CHRM3
SCHEMBL5953140 0.73 CHRM2 (0.30) CHRM3CHRM2CHRM1
SCHEMBL5953142 0.73 CHRM2 (0.30) CHRM3CHRM2CHRM1
SCHEMBL4418336 0.73 CHRM2 (0.30) CHRM3CHRM2CHRM1
SCHEMBL5953749 0.70 HTR5A (0.33)
SCHEMBL5953746 0.70 HTR5A (0.33)
SCHEMBL9313946 0.69
SCHEMBL214300 0.69
SCHEMBL15473844 0.68 HRH3 (0.33) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1211940-A1 AZABICYCLO AND AZACYCLO OXIME AND AMINE COMPOUNDS AS PESTICIDES Aventis CropScience GmbH (DE) 2002-06-12 EP disclosed
WO-2001015532-A1 AZABICYCLO AND AZACYCLO OXIME AND AMINE COMPOUNDS AS PESTICIDES AVENTIS CROPSCIENCE GMBH (DE) 2001-03-08 WO disclosed