Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090784 | 0.85 | ADRB3 (0.62) | ADRB3ADRB1ADRB2KCNH2 | |
| SCHEMBL7092202 | 0.85 | ADRB3 (0.76) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7699559 | 0.83 | ADRB1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7091815 | 0.82 | ADRB3 (0.76) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7570375 | 0.81 | ADRB3 (0.67) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7095222 | 0.80 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7700958 | 0.80 | ADRB3 (0.60) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7092642 | 0.80 | ADRB3 (0.60) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7094940 | 0.80 | ADRB3 (0.74) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7097086 | 0.80 | ADRB3 (0.60) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |