Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.72 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940321 | 0.86 | PIN1 (0.67) | PIN1KDM4EALDH1A1NPY5RSCN2A | |
| SCHEMBL3057838 | 0.84 | PIN1 (1.00) | PIN1NPY5RSCN2ATP53 | |
| SCHEMBL14953213 | 0.83 | PIN1 (0.72) | PIN1TNKSTNKS2MAPK14NPY5R | |
| SCHEMBL17868506 | 0.83 | PIN1 (0.72) | PIN1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL17868429 | 0.83 | PIN1 (0.72) | PIN1MMP2MMP9MMP13KDM4E | |
| Hydrochloric Acid SCHEMBL27325075 | 0.81 | PIN1 (0.70) | PIN1KDM4EALDH1A1TNKSTNKS2 | |
| SCHEMBL23846993 | 0.79 | PIN1 (0.66) | PIN1KDM4EALDH1A1SCN2ARXFP1 | |
| SCHEMBL3592405 | 0.73 | PIN1 (0.63) | PIN1KDM4EALDH1A1PTGESMAPT | |
| SCHEMBL25754942 | 0.73 | PIN1 (0.63) | PIN1DHODH | |
| SCHEMBL4893631 | 0.73 | PIN1 (0.66) | PIN1MMP2MMP9MMP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066477-A2 | IMIDAZOPYRIDINES | ASTRAZENECA AB (SE) | 2002-08-29 | — | — | WO | disclosed |