Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087007 | 0.92 | TACR1 (0.58) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7673246 | 0.92 | TACR1 (0.58) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7089245 | 0.89 | TACR1 (0.68) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7653308 | 0.88 | TACR1 (0.58) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7087794 | 0.88 | TACR1 (0.62) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7088811 | 0.88 | TACR1 (0.56) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7668974 | 0.88 | TACR1 (0.53) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7090456 | 0.88 | TACR1 (0.61) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7091686 | 0.88 | TACR1 (0.69) | TACR1MAPTP2RY14MEN1KMT2A | |
| SCHEMBL7084238 | 0.87 | TACR1 (0.63) | TACR1MAPTP2RY14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339094-B1 | FOR THERAPY OF CONDITION ASSOCIATED WITH AN EXCESS OF TACHYKININS SUCH AS MIGRANE HEADACHES | ELI LILLY AND COMPANY | 2002-01-15 | — | — | US | disclosed |