Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700127 | 1.00 | KDM4E (0.36) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL7700122 | 0.76 | HTT (0.36) | KDM4EHTTGAA | |
| SCHEMBL7705140 | 0.76 | HTT (0.38) | KDM4EHTTGAA | |
| SCHEMBL7705141 | 0.76 | HTT (0.38) | KDM4EHTTGAA | |
| SCHEMBL1310629 | 0.75 | HDAC1 (0.52) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL2154529 | 0.75 | HDAC1 (0.52) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL633115 | 0.75 | HTT (0.42) | KDM4ESMN1; SMN2HTTMAPTGAA | |
| SCHEMBL16852916 | 0.71 | KMT2A (0.42) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL16831975 | 0.71 | KMT2A (0.42) | KDM4EKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL14789416 | 0.69 | CDK5 (0.42) | KDM4EKMT2ASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355665-B1 | ANTIHISTAMINES, ANTIALLERGENS AND IRRITABLE BOWEL SYNDROME. | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-03-12 | — | — | US | disclosed |