SCHEMBL7700142

SCHEMBL7700142

CNC(=O)C(=NOC)c1ccccc1CON=C(C)C1CC1c1c(CCl)cccc1CCl

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.39
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156654 0.91 HIF1A (0.39) HIF1APTGS2
SCHEMBL6156658 0.91 HIF1A (0.39) HIF1APTGS2
SCHEMBL6225395 0.85 HIF1A (0.43) HIF1A
SCHEMBL6225394 0.85 HIF1A (0.43) HIF1A
SCHEMBL6156508 0.81 HIF1A (0.48) HIF1APTGS2
SCHEMBL6158168 0.81 HIF1A (0.48) HIF1APTGS2
SCHEMBL7700157 0.81 HIF1A (0.48) HIF1APTGS2
SCHEMBL6156945 0.81 HIF1A (0.48) HIF1APTGS2
SCHEMBL6155978 0.81 HIF1A (0.48) HIF1APTGS2
SCHEMBL6224353 0.81 HIF1A (0.44) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348627-B1 CONTROLLING PHYTOPATHOGENIC FUNGI DOW AGROSCIENCES LLC 2002-02-19 US claimed