Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.36 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694263 | 0.80 | DPP7 (0.54) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL6234774 | 0.79 | ARG1 (0.35) | DPP7DPP4LMNA | |
| SCHEMBL6234770 | 0.79 | ARG1 (0.35) | DPP7DPP4LMNA | |
| SCHEMBL30819305 | 0.77 | DPP4 (0.46) | DPP7DPP4DPP8FAPDPP9 | |
| Bromide SCHEMBL7271475 | 0.76 | DPP4 (0.45) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL9725095 | 0.74 | ACE (0.55) | DPP7DPP4LMNADPP8FAP | |
| SCHEMBL9725100 | 0.74 | ACE (0.55) | DPP7DPP4LMNADPP8FAP | |
| SCHEMBL7699816 | 0.74 | DPP4 (0.44) | DPP7DPP4DPP8FAPDPP9 | |
| SCHEMBL7694794 | 0.70 | DPP4 (0.54) | DPP4ACE | |
| SCHEMBL30051953 | 0.70 | ACE (0.50) | DPP4LMNAACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |