Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700997 | 0.90 | LRRK2 (0.55) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL7696350 | 0.89 | LRRK2 (0.53) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL7695719 | 0.89 | LRRK2 (0.53) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL7699518 | 0.88 | KDM4E (0.57) | LRRK2KDM4EHSD17B10HTTDYRK1A | |
| SCHEMBL7697867 | 0.88 | DYRK1A (0.54) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL8990998 | 0.88 | LRRK2 (0.56) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL8991109 | 0.87 | KDM4E (0.59) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL7703709 | 0.87 | LRRK2 (0.49) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL8991293 | 0.84 | GLA (0.58) | LRRK2KDM4EHSD17B10TSHRHTT | |
| SCHEMBL8991189 | 0.84 | LRRK2 (0.52) | LRRK2KDM4EHSD17B10TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |