Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700997 | 0.90 | LRRK2 (0.55) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7696350 | 0.88 | LRRK2 (0.53) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7695719 | 0.88 | LRRK2 (0.53) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7701567 | 0.88 | LRRK2 (0.50) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7700326 | 0.87 | LRRK2 (0.52) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991102 | 0.87 | DYRK1A (0.56) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8990998 | 0.87 | LRRK2 (0.56) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991072 | 0.86 | LRRK2 (0.51) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL8991158 | 0.85 | KMT2A (0.49) | KDM4ETSHRMAPK1HTTHSD17B10 | |
| SCHEMBL7698547 | 0.85 | LRRK2 (0.56) | KDM4ETSHRMAPK1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |