Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 8/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698643 | 0.92 | NR1H2 (0.35) | NR1H2NR1H3EGFRPDE4APDE4B | |
| SCHEMBL7699521 | 0.90 | PDE4A (0.35) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7703112 | 0.89 | NR1H2 (0.38) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7699082 | 0.88 | MCHR1 (0.43) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7698759 | 0.86 | PDE4A (0.38) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7694958 | 0.81 | NR1H3 (0.44) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7700309 | 0.80 | MCHR1 (0.44) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7693775 | 0.80 | MCHR1 (0.44) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7700767 | 0.80 | MCHR1 (0.42) | NR1H2NR1H3PDE4APDE4BPDE4C | |
| SCHEMBL7700341 | 0.80 | PDE4B (0.38) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |