Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 5/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | TEK | Q02763 | 3/20 | 0.45 |
| ▸ | RET | P07949 | 5/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16747748 | 0.83 | RET (0.58) | SRCADKLCKKDRTEK | |
| SCHEMBL7701691 | 0.77 | KDR (0.49) | SRCADKLCKKDRTEK | |
| SCHEMBL19732639 | 0.75 | RET (0.58) | SRCLCKKDRTEKRET | |
| SCHEMBL6223045 | 0.74 | PDGFRB (0.57) | SRCLCKKDRTEKRET | |
| SCHEMBL18100426 | 0.73 | ADK (0.55) | SRCADKLCKKDRRET | |
| SCHEMBL7701218 | 0.72 | RET (0.52) | SRCADKLCKKDRTEK | |
| SCHEMBL13269011 | 0.72 | ADORA2A (0.65) | PIK3CDEGFRPI4KB | |
| SCHEMBL13268766 | 0.72 | ADORA2A (0.65) | PIK3CDEGFRPI4KB | |
| SCHEMBL1942060 | 0.72 | PDGFRB (0.66) | SRCLCKKDRTEKRET | |
| SCHEMBL7701013 | 0.71 | ADORA2A (0.53) | SRCADKLCKKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |