⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741512 | 0.73 | — | — | |
| SCHEMBL7732735 | 0.73 | — | — | |
| SCHEMBL7739710 | 0.73 | — | — | |
| SCHEMBL7738706 | 0.73 | — | — | |
| SCHEMBL7737767 | 0.73 | — | — | |
| SCHEMBL7658464 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL247765 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL496915 | 0.69 | — | — | |
| SCHEMBL261952 | 0.69 | — | — | |
| SCHEMBL7671023 | 0.65 | TRIM24 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995567-B | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-111995567-A | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2020-11-27 | — | — | CN | disclosed |
| CN-100503608-C | Deazapurines and their use | EISAI CO LTD (JP) | 2009-06-24 | — | — | CN | disclosed |
| CN-100484973-C | Substituted indenyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-05-06 | — | — | CN | disclosed |
| CN-1643004-A | Substituted indenyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-07-20 | — | — | CN | disclosed |
| CN-1630657-A | Deazapurines and their use | EISAI CO LTD (JP) | 2005-06-22 | — | — | CN | disclosed |
| WO-2002057257-A1 | CYCLO`C!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREFOR | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |