Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700054 | 0.91 | NPC1 (0.50) | ALDH1A1HPGDDGAT1CNR1CNR2 | |
| SCHEMBL7693811 | 0.91 | NPC1 (0.50) | ALDH1A1HPGDDGAT1CNR1CNR2 | |
| SCHEMBL7695821 | 0.89 | ECE1 (0.49) | HPGDDGAT1CNR1CNR2EPHX2 | |
| SCHEMBL7693513 | 0.89 | DGAT1 (0.48) | ALDH1A1HPGDDGAT1CNR1CNR2 | |
| SCHEMBL7693795 | 0.89 | KDM4E (0.51) | ALDH1A1DGAT1CNR1CNR2EPHX2 | |
| SCHEMBL7700507 | 0.88 | DGAT1 (0.47) | ALDH1A1HPGDDGAT1CNR1CNR2 | |
| SCHEMBL7696225 | 0.88 | EPHX2 (0.45) | ALDH1A1HPGDDGAT1CNR1CNR2 | |
| SCHEMBL7699624 | 0.87 | DGAT1 (0.47) | ALDH1A1HPGDDGAT1CNR1CNR2 | |
| SCHEMBL7702160 | 0.87 | EPHX2 (0.44) | DGAT1CNR1CNR2EPHX2HSD17B10 | |
| SCHEMBL7700947 | 0.87 | KDM4E (0.47) | ALDH1A1DGAT1CNR1CNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |