Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.71 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7698457 | 0.87 | SLC6A9 (0.77) | SLC6A9TRPV1PPARDGRIN2BGRIN1 | |
| Org-25935 SCHEMBL7703430 | 0.83 | SLC6A9 (1.00) | SLC6A9PPARDGRIN2BGRIN1TAS2R14 | |
| Org-25935 SCHEMBL27034881 | 0.83 | SLC6A9 (1.00) | SLC6A9PPARDGRIN2BGRIN1TAS2R14 | |
| Org-25935 SCHEMBL1761267 | 0.83 | SLC6A9 (1.00) | SLC6A9PPARDGRIN2BGRIN1TAS2R14 | |
| Org-25935 SCHEMBL7703262 | 0.82 | SLC6A9 (0.98) | SLC6A9PPARDGRIN2BGRIN1TAS2R14 | |
| SCHEMBL7700175 | 0.82 | SLC6A9 (0.75) | SLC6A9GRIN2BGRIN1 | |
| SCHEMBL7704292 | 0.82 | SLC6A9 (0.75) | SLC6A9GRIN2BGRIN1 | |
| SCHEMBL19501070 | 0.81 | SLC6A9 (0.88) | SLC6A9PPARDGRIN2BGRIN1TAS2R14 | |
| Hydrochloric Acid SCHEMBL7411298 | 0.81 | SLC6A9 (0.60) | SLC6A9TRPV1PPARDGRIN2BGRIN1 | |
| SCHEMBL16714469 | 0.81 | SLC6A9 (0.76) | SLC6A9PPARDGRIN2BGRIN1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |