SCHEMBL7700671

SCHEMBL7700671

C=COCC=CCC=CCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.40
ALDH1A1 P00352 6/20 0.34
CYP19A1 P11511 4/20 0.34
PPARG P37231 3/20 0.34
OXER1 Q8TDS5 3/20 0.34
MAPT P10636 3/20 0.34
RXRA P19793 2/20 0.34
FFAR1 O14842 2/20 0.34
F7 P08709 3/20 0.32
F3 P13726 3/20 0.32
PPARA Q07869 3/20 0.32
ADORA3 P0DMS8 2/20 0.32
NR1I2 O75469 2/20 0.32
PTGS2 P35354 2/20 0.32
KMT2A Q03164 2/20 0.32
PPARD Q03181 2/20 0.32
PGR P06401 1/20 0.32
PDE4D Q08499 1/20 0.32
CYP3A4 P08684 2/20 0.31
ALOX15 P16050 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5134024 0.77
SCHEMBL16784559 0.73
SCHEMBL7706545 0.73
SCHEMBL8581303 0.72
SCHEMBL17062954 0.72 ALDH1A1 (0.50) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL3683481 0.72
SCHEMBL4302373 0.72
SCHEMBL17062956 0.72 ALDH1A1 (0.50) PTGS1ALDH1A1CYP19A1PPARGOXER1
SCHEMBL6473740 0.72
SCHEMBL6474272 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0909298-B1 STABILISATION OF PAINTS WITH SPIROINDANE DERIVATIVES VANTICO AG (CH) 2002-10-23 EP disclosed
US-6197861-B1 Stabilization of paints with spiroindane derivatives VANTICO INC. 2001-03-06 US disclosed
EP-0909298-A1 STABILISATION OF PAINTS WITH SPIROINDANE DERIVATIVES Ciba SC Holding AG (CH) 1999-04-21 EP disclosed
WO-1998001507-A1 STABILISATION OF PAINTS WITH SPIROINDANE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-01-15 WO disclosed
US-5262072-A Stabilization of a lubricant or hydraulic fluid against oxidation and/or heat degradation CIBA-GEIGY CORPORATION (US) 1993-11-16 US disclosed