Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 19/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 18/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091738 | 1.00 | ADRB1 (0.48) | ADRB1ADRB3ADRB2CA12CA1 | |
| SCHEMBL7092790 | 0.89 | ADRB3 (0.58) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7575464 | 0.89 | ADRB3 (0.58) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7094287 | 0.89 | ADRB3 (0.57) | ADRB1ADRB3ADRB2CA12CA1 | |
| SCHEMBL7235449 | 0.89 | ADRB1 (0.42) | ADRB1ADRB3ADRB2CA12CA1 | |
| SCHEMBL7091408 | 0.89 | ADRB1 (0.42) | ADRB1ADRB3ADRB2CA12CA1 | |
| SCHEMBL7239947 | 0.87 | ADRB3 (0.46) | ADRB1ADRB3ADRB2CA12CA1 | |
| SCHEMBL7094942 | 0.86 | ADRB3 (0.57) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7575467 | 0.86 | ADRB1 (0.46) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7094015 | 0.84 | ADRB1 (0.61) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |