Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28157759 | 0.85 | DGAT1 (0.37) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL2218675 | 0.82 | GAA (0.47) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL16863947 | 0.82 | GAA (0.47) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL1445502 | 0.80 | POLB (0.54) | SMN1; SMN2ALDH1A1POLBNPSR1MEN1 | |
| SCHEMBL31410480 | 0.78 | GAA (0.53) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL24802924 | 0.75 | GAA (0.43) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL5704826 | 0.75 | GAA (0.43) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL1967314 | 0.74 | GAA (0.42) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL31381875 | 0.74 | GAA (0.49) | GAASMN1; SMN2ALDH1A1L3MBTL1GLA | |
| SCHEMBL19105228 | 0.73 | DGAT1 (0.36) | GAASMN1; SMN2ALDH1A1POLBNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020039769-A1 | Process for preparing optically active 3,3,3- trifluoromethyl-2-alkylpropionic acid derivatives | LONZA AG | 2002-04-04 | — | — | US | claimed |
| US-20020039769-A1 | Process for preparing optically active 3,3,3- trifluoromethyl-2-alkylpropionic acid derivatives | LONZA AG | 2002-04-04 | — | — | US | disclosed |